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Twenty-marker hormone and wellbeing panel covering sex hormones, adrenal, thyroid, metabolic, and nutritional markers in a single assessment.
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A 20-marker comprehensive hormone and wellbeing panel covering sex hormones, adrenal markers, thyroid function, metabolic indicators.
The Comprehensive Hormone and Wellbeing Panel brings together 20 carefully selected markers across five domains to give the most complete private hormone picture available in a single assessment.
Sex hormones: oestradiol, progesterone, testosterone (total and free), SHBG, LH, FSH, prolactin, and dehydroepiandrosterone sulphate (DHEA-S).
Adrenal: cortisol and ACTH.
Thyroid: TSH, FT4, and FT3.
Metabolic: fasting insulin, HbA1c, and adiponectin.
Nutritional: vitamin D and ferritin.
This panel is designed for people who want a single, comprehensive assessment rather than multiple separate panels. It is ideal for those experiencing complex, multi-system symptoms that do not fit a single hormonal category — such as chronic fatigue with hormonal, adrenal, thyroid, and nutritional contributors all potentially at play. It is also used as a comprehensive annual baseline by people who want to understand and monitor their overall hormonal health in depth.
Venous blood draw required; morning collection essential for accurate cortisol and testosterone. GMC-physician reviewed results within 5 to 7 working days. Available for both men and women — reference ranges are sex- and age-specific.
Understand what each marker measures, why it matters, and what the science says — not just a list of numbers.
Primary oestrogen; fluctuates during perimenopause and is a driver of many sex-hormone-related symptoms.
Post-ovulation balancing hormone; low relative to oestradiol indicates oestrogen dominance or anovulatory cycles.
Primary androgen affecting libido, energy, muscle mass, and mood in both men and women.
Biologically active testosterone fraction; determined by total testosterone and SHBG together.
Carrier protein governing bioavailability of testosterone and oestradiol.
Pituitary trigger for ovulation and testosterone production; contextualises sex hormone results.
Pituitary signal for follicle development and sperm production; rises with declining ovarian or testicular reserve.
Pituitary hormone that suppresses reproductive function when chronically elevated outside of breastfeeding.
Adrenal androgen precursor; declines with age and with adrenal stress burden.
Primary stress hormone; morning peak value assesses adrenal reserve and HPA axis function.
Pituitary signal that drives cortisol production; together with cortisol, distinguishes primary from secondary adrenal dysfunction.
Primary thyroid screening marker; the pituitary signal that governs thyroid hormone output.
Main thyroid hormone secreted by the gland; precursor to the active FT3.
Active thyroid hormone; reflects conversion efficiency and cellular thyroid action.
Earliest biochemical indicator of insulin resistance when elevated in the fasted state.
Three-month average blood glucose; identifies pre-diabetic trends and chronic glycaemic burden.
Insulin-sensitising, anti-inflammatory adipokine; paradoxically low in obesity and metabolic syndrome.
Immune regulator linked to thyroid antibody burden, mood, bone health, and metabolic function.
Iron storage protein; low levels impair thyroid hormone production and T4-to-T3 conversion.
This panel is designed for adults who want a comprehensive, evidence-based picture of their metabolic health — not a GP referral panel.
Those experiencing multi-system symptoms not adequately explained by a single-category panel
People wanting a comprehensive annual hormone baseline for proactive health management
Women in perimenopause with complex overlapping symptoms
Men with fatigue, low libido, and metabolic concerns wanting a single thorough assessment
A 20-marker panel generates a large volume of data, and out-of-range values must be interpreted in context rather than in isolation. Not all elevated or low values are clinically significant; some represent natural variation or are explained by concurrent findings in the same panel. ACTH is highly labile and requires rapid sample processing, making early morning clinic collection essential. Fasting insulin is a screening indicator rather than a definitive test for insulin resistance. This panel does not include thyroid antibodies, Reverse T3, AMH, aldosterone, or detailed nutritional markers such as B12, folate, magnesium, or zinc; additional testing may be advised based on these results. The physician report will prioritise findings and recommend next steps clearly.
From order to physician-reviewed report in as little as three working days.
Three options designed to fit your schedule, location, and preference — all producing a laboratory-standard sample.
Adults 18+ in mainland UK. Not suitable if you have had a transfusion in the last 3 months.
Order anytime; kit dispatched within 24 hours Mon–Fri.
Allow 24–48 hours for sample transit on top of lab processing time.
Adults 18+ within 20 miles of a serviced city centre.
Mon–Sun, 06:00–20:00. Next-day booking typical.
Sample reaches the lab within 24 hours of collection.
Adults 16+ with photo ID. Paediatric draws by appointment at selected sites.
Mon–Fri, with Saturday hours at most metropolitan locations.
Samples processed same-day at the receiving clinic.
Every test is processed in a UKAS ISO 15189-accredited laboratory, overseen by GMC-registered physicians, and governed by UK GDPR. No overseas processing, no offshore data.
Follow these guidelines to ensure accurate, reproducible results. Most markers are sensitive to recent food, exercise, and sleep.
Can't find your answer? Our clinical support team is available Monday to Friday, 9am–5pm.
Contact supportThe Comprehensive Hormone and Wellbeing Panel is most valuable for people who have tried to identify the root cause of complex, multi-system symptoms through single-category testing without finding a clear answer, or who want to conduct a thorough annual baseline review rather than multiple separate panels. It is particularly useful for those with overlapping fatigue, hormonal, thyroid, and metabolic concerns — where the interplay between systems is as important as any individual marker. It is also used by those who are preparing for or monitoring HRT, managing complex menopause, or optimising performance and longevity.
Trupoint Health’s GMC-registered reviewing physicians are experienced in interpreting multi-marker hormonal panels. Rather than flagging every out-of-range value in isolation, the physician report considers the pattern of results together — for example, recognising that low cortisol with elevated ACTH and low dehydroepiandrosterone sulphate (DHEA-S) together suggest HPA axis dysfunction, rather than commenting on each marker separately. The report is structured to highlight the most clinically significant findings, explain how they interact, and provide clear actionable recommendations, prioritised by clinical urgency.
Yes. The panel includes markers relevant to male physiology — testosterone (total and free), SHBG, LH, FSH, prolactin, and dehydroepiandrosterone sulphate (DHEA-S) alongside adrenal, thyroid, metabolic, and nutritional markers. Reference ranges are sex-specific. For men, oestradiol is included because it is clinically relevant for bone health, cardiovascular function, and sexual function. The panel provides a comprehensive hormonal overview applicable to men of any age, from those optimising health in their 30s through to older men managing testosterone decline, metabolic risk, or HRT monitoring.
Yes. A full 10 to 12 hour fast is required before collection because several of the included markers (fasting insulin, fasting glucose component of insulin resistance calculation, ACTH, and cortisol) are significantly influenced by food intake. Testosterone and SHBG are also best measured fasted and in the morning. Collecting in this standardised fasted morning window ensures all 20 markers are obtained under optimal and consistent conditions, making the results both accurate and comparable for future retesting.
Annual reassessment is recommended for most people using this panel as a monitoring tool. If significant out-of-range values are identified and interventions are underway (nutritional, pharmacological, or lifestyle), a 3 to 6 month follow-up on the specific markers of concern (rather than the full 20-marker panel) is more practical and cost-effective. Your physician report will recommend a specific retesting timeline based on your individual results. For those using this as part of ongoing longevity or performance monitoring, annual testing provides a meaningful trend across multiple hormonal axes simultaneously.
Yes, and we encourage it. The Trupoint Health results report is formatted for clinical legibility — it includes reference ranges, physician narrative, and recommended next steps. Your GP may or may not act on private test results, but having this data can prompt more informed conversations, support a referral request, or supplement NHS monitoring. Some GPs actively welcome comprehensive private baseline data as a starting point for more targeted NHS investigation. You can download and share your full results directly from your Trupoint Health dashboard.
