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12-marker pre-conception panel covering immunity, haematology, thyroid, nutrition, and reproductive hormones for women planning pregnancy.
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A 12-marker pre-conception health panel for women planning pregnancy — combining rubella and varicella immunity, full blood count, ferritin, thyroid function.
Planning a pregnancy is one of the most important health decisions a woman makes. The Pre-Conception Female Health Screen identifies modifiable and non-modifiable health factors that can affect the chance of conception and the course of pregnancy.
Immunity: rubella (German measles) and varicella (chickenpox) immunity are screened because infection during pregnancy can cause serious fetal harm. Non-immune women should receive vaccination before conceiving.
Haematology: full blood count screens for anaemia — iron-deficiency and B12-related — which should be corrected before pregnancy as demand increases substantially.
Nutritional: ferritin and vitamin D — both essential for healthy fetal development and maternal wellbeing during pregnancy.
Thyroid: TSH — because thyroid demand increases early in pregnancy, and starting with a TSH above 2.5 mIU/L increases the risk of thyroid dysfunction, miscarriage, and fetal neurodevelopmental impairment.
Hormonal: AMH (ovarian reserve), FSH and LH (ovarian function), and prolactin (common treatable cause of anovulation).
Venous draw required. GMC-physician reviewed results within 5 to 7 working days.
Understand what each marker measures, why it matters, and what the science says — not just a list of numbers.
Screens for immunity to German measles; rubella infection in early pregnancy causes severe fetal abnormalities.
Screens for immunity to chickenpox; primary varicella in pregnancy carries significant fetal and maternal risk.
Screens for anaemia before pregnancy, when iron and haematological demands increase substantially.
Iron stores; should ideally be above 30 mcg/L before conception to support fetal development and maternal wellbeing.
Target TSH below 2.5 mIU/L before conception; thyroid demand increases markedly in early pregnancy.
Adds context to TSH — particularly valuable if TSH is borderline or symptoms are present.
Essential for fetal bone and immune development; deficiency is extremely common in UK women.
Ovarian reserve marker; provides context for fertility timeline and response to ovarian stimulation if needed.
Baseline pituitary signal for ovarian function; elevated FSH suggests declining ovarian reserve.
Elevated LH-to-FSH ratio suggests PCOS; LH contextualises FSH in ovarian assessment.
Baseline oestradiol contextualises FSH and confirms the follicular phase hormonal environment.
Screens for hyperprolactinaemia — a common, treatable cause of anovulation and implantation failure.
This panel is designed for adults who want a comprehensive, evidence-based picture of their metabolic health — not a GP referral panel.
Women planning to start trying to conceive in the next 3 to 12 months
Those who have never been immunity-checked for rubella or varicella
Women who want a comprehensive health baseline before pregnancy
Those with previous anaemia, thyroid issues, or fertility concerns wanting reassurance
This panel does not include: antiphospholipid antibodies, BRCA screening, chromosomal analysis, or carrier testing for genetic conditions. Immunity markers detect the presence of IgG antibodies; they confirm immunity status but do not quantify the degree of immunity or predict vaccine response. Women found to be non-immune to rubella or varicella should be vaccinated before conceiving and should avoid pregnancy for at least 4 weeks after each MMR or varicella vaccine dose. Prolactin is stress-sensitive and a single elevated result should be confirmed before acting on it. Please share results with your GP before attempting to conceive, particularly if thyroid abnormalities or non-immunity are identified.
From order to physician-reviewed report in as little as three working days.
Three options designed to fit your schedule, location, and preference — all producing a laboratory-standard sample.
Adults 18+ in mainland UK. Not suitable if you have had a transfusion in the last 3 months.
Order anytime; kit dispatched within 24 hours Mon–Fri.
Allow 24–48 hours for sample transit on top of lab processing time.
Adults 18+ within 20 miles of a serviced city centre.
Mon–Sun, 06:00–20:00. Next-day booking typical.
Sample reaches the lab within 24 hours of collection.
Adults 16+ with photo ID. Paediatric draws by appointment at selected sites.
Mon–Fri, with Saturday hours at most metropolitan locations.
Samples processed same-day at the receiving clinic.
Every test is processed in a UKAS ISO 15189-accredited laboratory, overseen by GMC-registered physicians, and governed by UK GDPR. No overseas processing, no offshore data.
Follow these guidelines to ensure accurate, reproducible results. Most markers are sensitive to recent food, exercise, and sleep.
Can't find your answer? Our clinical support team is available Monday to Friday, 9am–5pm.
Contact supportRubella (German measles) causes congenital rubella syndrome in babies exposed in the womb, particularly during the first trimester. This can result in hearing loss, cataracts, heart defects, intellectual disability, and other serious complications. In the UK, most adults have received two doses of the MMR vaccine (measles, mumps, rubella) and are immune — but immunity can occasionally wane or may never have been established. Checking immunity before conception allows non-immune women to receive a booster and achieve protective immunity before pregnancy, since the MMR is a live vaccine that cannot be given during pregnancy.
If your result shows you are not immune to rubella or varicella (IgG antibody negative), you should discuss MMR and varicella vaccination with your GP before conceiving. The MMR vaccine requires two doses (if you have had none) or a single booster if partially immune. The varicella vaccine also requires two doses if not previously vaccinated. Both are live attenuated vaccines and are contraindicated during pregnancy. After each MMR dose, avoid conception for at least 4 weeks. After the varicella vaccine, avoid conception for at least 3 months. Vaccination is highly effective and will establish immunity before your next attempt to conceive.
Haemoglobin only falls when iron stores (measured by ferritin) are already significantly depleted — anaemia is a late-stage manifestation of iron deficiency. Iron demand in pregnancy is substantial: approximately 1,000 mg of additional iron is needed, primarily in the second and third trimesters, to support fetal growth, placental development, and the expanded maternal blood volume. Starting pregnancy with optimal ferritin stores (ideally above 30 mcg/L, with above 70 mcg/L being ideal) means the body has adequate reserves to meet this demand without becoming anaemic. Low ferritin before pregnancy — even with normal haemoglobin — increases the risk of maternal iron deficiency anaemia in the third trimester.
Vitamin D deficiency in pregnancy is associated with increased risks of pre-eclampsia, gestational diabetes, low birth weight, and impaired fetal bone development. Before conception, the NHS recommends all adults take 400 IU (10 mcg) of vitamin D daily. For women who are deficient (25-OH vitamin D below 50 nmol/L), higher supplemental doses (typically 1,000 to 4,000 IU daily) under medical guidance may be needed to achieve optimal levels. A vitamin D level above 75 nmol/L is generally considered optimal for pregnancy. Testing before conception allows you to identify and correct deficiency with adequate lead time.
Yes, ideally. Hormonal contraception suppresses AMH by 20 to 30% and blunts FSH, LH, oestradiol, and prolactin, making the reproductive hormone results difficult to interpret. For the most accurate fertility markers, we recommend testing at least 3 months after stopping hormonal contraception. If you are planning to stop the pill soon in preparation for trying to conceive, testing 3 months after stopping gives a meaningful hormonal baseline. If you need results sooner, the immunity, haematological, thyroid, and nutritional markers are all unaffected by hormonal contraception and remain fully interpretable.
Your physician report will flag TSH values above 2.5 mIU/L in the context of pre-conception planning and will recommend a GP discussion. For women with TSH between 2.5 and 4.0 mIU/L, the clinical decision about whether to start low-dose levothyroxine before conception is nuanced and depends on the full thyroid picture (FT4, symptoms, antibody status if available). NICE guidelines recommend treating overt hypothyroidism (TSH above 4.0 mIU/L) before conception. For borderline TSH, many fertility specialists and GPs recommend a trial of low-dose levothyroxine to optimise TSH below 2.5 mIU/L before actively trying to conceive.
