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Thirty-plus markers. Six physiological domains. One integrated picture of your biological age and health trajectory.
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Our most comprehensive preventative health and longevity screen. 30-plus markers covering metabolic health, full hormonal axis, cardiovascular risk.
This panel represents the most thorough preventative health assessment we offer. Spanning over thirty biomarkers across six physiological domains, it gives a complete and nuanced picture of where the body is ageing well and where it is accumulating risk. Metabolic assessment includes fasting glucose, HbA1c, fasting insulin, HOMA-IR, and the full lipoprotein profile including ApoB and Lp(a). Hormonal assessment covers the full sex hormone axis (testosterone, oestradiol, SHBG, dehydroepiandrosterone sulphate (DHEA-S), LH, FSH, prolactin), thyroid function (TSH, free T4, free T3), and the growth axis (IGF-1, cortisol). Inflammatory status is captured via hs-CRP, homocysteine, fibrinogen, and ESR. Organ function is assessed via liver enzymes, kidney markers, and full blood count. Micronutrient status rounds out the picture with vitamin D, B12, and ferritin. Every result is reviewed by a GMC-registered physician, and the accompanying report synthesises the findings into an integrated longevity commentary.
Understand what each marker measures, why it matters, and what the science says — not just a list of numbers.
This panel is designed for adults who want a comprehensive, evidence-based picture of their metabolic health — not a GP referral panel.
Individuals who treat their health as a long-term investment and want the most complete picture available
Adults over 45 planning a comprehensive annual review
Those engaged with a longevity medicine practitioner or functional medicine GP
Biohackers and quantified-self enthusiasts building a longitudinal health dataset
Anyone who has had concerning results on a simpler panel and wants a full picture before a clinical appointment
A panel of 30-plus markers produces a breadth of data that increases the probability of results outside the reference range by chance alone. In a healthy individual, approximately 5 percent of results will fall outside the 95th-percentile reference range simply due to statistical variation. This panel is therefore intended to be interpreted as a whole by a clinician rather than treated as a series of isolated findings. Lp(a) and certain genetic lipid disorders are identified but not treatable with current standard therapies; these findings should prompt specialist cardiovascular referral. Epigenetic biological age assessment (e.g., DNA methylation clocks) is not part of this panel and requires specialist laboratory processing.
From order to physician-reviewed report in as little as three working days.
Venous draw required for the full 30-plus marker panel.
Water permitted. No supplements or medications on the morning of collection.
Priority processing within 24 hours of receipt.
Physician commentary and integrated summary in 3 to 5 working days.
Three options designed to fit your schedule, location, and preference — all producing a laboratory-standard sample.
Adults 18+ in mainland UK. Not suitable if you have had a transfusion in the last 3 months.
Order anytime; kit dispatched within 24 hours Mon–Fri.
Allow 24–48 hours for sample transit on top of lab processing time.
Adults 18+ within 20 miles of a serviced city centre.
Mon–Sun, 06:00–20:00. Next-day booking typical.
Sample reaches the lab within 24 hours of collection.
Adults 16+ with photo ID. Paediatric draws by appointment at selected sites.
Mon–Fri, with Saturday hours at most metropolitan locations.
Samples processed same-day at the receiving clinic.
Every test is processed in a UKAS ISO 15189-accredited laboratory, overseen by GMC-registered physicians, and governed by UK GDPR. No overseas processing, no offshore data.
Follow these guidelines to ensure accurate, reproducible results. Most markers are sensitive to recent food, exercise, and sleep.
Can't find your answer? Our clinical support team is available Monday to Friday, 9am–5pm.
Contact supportTraditional private health checks typically include standard lipid panels, fasting glucose, full blood count, and a few metabolic markers. This panel goes considerably further: it adds ApoB and Lp(a) for cardiovascular risk precision, fasting insulin and HOMA-IR for metabolic dysfunction detection, the full sex hormone and thyroid axis, IGF-1 and cortisol for anabolic-catabolic balance, and inflammatory markers beyond standard CRP. The goal is not simply to confirm normality within broad NHS reference ranges but to identify the early metabolic and hormonal trajectories associated with accelerated ageing and preventable disease.
Most standard thyroid panels include TSH and free T4. Free T3 (triiodothyronine) is the active thyroid hormone that acts at the cellular level. T4 is a prohormone that must be converted to T3 by deiodinase enzymes in peripheral tissues, particularly the liver and gut. In hypothyroidism treated with levothyroxine (T4-only replacement), some patients have normal TSH and free T4 but low free T3 due to impaired conversion, which can explain persistent symptoms. In functional or integrative medicine contexts, low-normal free T3 despite normal TSH is also considered a relevant longevity marker because T3 regulates mitochondrial function and thermogenesis.
Chronically elevated cortisol accelerates biological ageing through several mechanisms: it suppresses growth hormone and IGF-1 production (impairing tissue repair), increases visceral adiposity and insulin resistance, impairs immune function, reduces hippocampal neurogenesis (relevant to memory and cognitive ageing), and accelerates telomere shortening. Morning cortisol is the reference point because it represents the cortisol awakening response, which should peak within 30 to 45 minutes of waking in a healthy adrenal axis. Blunted or absent cortisol awakening response is associated with burnout and chronic fatigue; an excessively high flat cortisol is associated with chronic stress and hypercortisolaemia.
Yes. All Trupoint Health reports are formatted as clinical documents with reference ranges and physician commentary, making them suitable for sharing with your GP, specialist, or private physician. We provide your results in PDF format via your secure online dashboard, and you can download and share at any time. Some GP practices welcome patient-initiated private testing as it reduces demand on NHS pathology; others prefer to run their own tests. We recommend discussing results with a qualified clinician rather than self-interpreting, particularly for results outside the reference range.
Annual testing is appropriate for most healthy adults using this panel as a longevity baseline. If you are actively modifying your lifestyle, diet, or supplementation programme, retesting after four to six months provides meaningful feedback on whether your interventions are achieving the intended biological effect. Some markers, particularly metabolic and lipid markers, respond relatively quickly to intervention and are worth re-evaluating within a few months of a significant dietary change. Hormonal markers tend to change more slowly and may warrant annual or biannual tracking.
Your physician commentary will prioritise findings by clinical significance rather than listing every out-of-range result with equal weight. As noted, statistical chance will produce a small number of borderline results in any large panel. The physician will contextualise each finding in relation to the others and your clinical context, flagging those that require action, those that should be monitored, and those that are likely artefact or within acceptable variation. If significant findings emerge that require specialist input, the commentary will recommend the appropriate referral pathway.
