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Nine-marker hormonal and metabolic panel targeting the key biochemical features of polycystic ovary syndrome.
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A targeted nine-marker hormonal and metabolic screen designed to assess the key features of polycystic ovary syndrome — including androgens.
Polycystic ovary syndrome (PCOS) is the most common hormonal disorder affecting women of reproductive age, yet it is frequently underdiagnosed and misunderstood. Diagnosis requires clinical, ultrasound, and biochemical assessment — but the hormonal blood picture is central to confirming PCOS and understanding which features are dominant.
The PCOS Hormone Panel measures nine markers across four domains: androgens (total testosterone, free testosterone, dehydroepiandrosterone sulphate (DHEA-S)), pituitary hormones (LH and FSH), reproductive hormones (oestradiol and SHBG), and metabolic markers (fasting insulin and HbA1c). Thyroid function is included because hypothyroidism can mimic PCOS and worsen its metabolic features.
This panel helps identify whether androgen excess is the dominant feature of your PCOS, whether insulin resistance is a major driver, and whether thyroid dysfunction may be contributing. All of these factors significantly affect management approach.
Venous blood draw required. Book a mobile phlebotomist or partner clinic appointment. GMC-physician reviewed results within 3 to 5 working days.
Understand what each marker measures, why it matters, and what the science says — not just a list of numbers.
Primary androgen; elevated in around 60% of women with PCOS and associated with acne, hair growth, and irregular cycles.
Biologically active fraction of testosterone; more sensitive than total testosterone for detecting mild androgen excess.
Adrenal androgen that distinguishes adrenal from ovarian androgen excess when both testosterone and dehydroepiandrosterone sulphate (DHEA-S) are elevated.
Elevated LH relative to FSH is a classic PCOS pattern, driving excess androgen production from the ovaries.
Used in context with LH to calculate the LH-to-FSH ratio; helps characterise the pituitary dysfunction in PCOS.
Assesses oestrogen environment; in PCOS, oestradiol may be elevated relative to cycle phase due to increased peripheral conversion.
Low SHBG — common in PCOS due to insulin resistance — amplifies free androgen activity and worsens symptoms.
Elevated fasting insulin indicates insulin resistance, a central metabolic feature of PCOS that drives androgen excess.
Three-month average blood glucose; assesses whether insulin resistance has progressed towards impaired glucose tolerance.
Screens for hypothyroidism, which can cause cycle irregularity and worsen PCOS-like metabolic features.
This panel is designed for adults who want a comprehensive, evidence-based picture of their metabolic health — not a GP referral panel.
Women with irregular or absent periods investigating a possible PCOS diagnosis
Those experiencing acne, unwanted facial or body hair, or hair thinning on the scalp
Women with unexplained weight gain or difficulty losing weight
Those trying to conceive with irregular cycles or anovulation
This panel provides biochemical data to support PCOS assessment but cannot diagnose PCOS on its own. Diagnosis requires the Rotterdam criteria, which include at least two of: irregular cycles, clinical or biochemical androgen excess, and polycystic ovarian morphology on ultrasound. Blood tests alone cannot assess ovarian morphology. Fasting insulin is not a standardised diagnostic test for insulin resistance and should be interpreted alongside clinical features and an OGTT if insulin resistance is confirmed. This panel does not include prolactin, which should be excluded as a cause of irregular cycles before a PCOS diagnosis is confirmed. Please share results with a GP or gynaecologist for clinical interpretation.
From order to physician-reviewed report in as little as three working days.
Three options designed to fit your schedule, location, and preference — all producing a laboratory-standard sample.
Adults 18+ in mainland UK. Not suitable if you have had a transfusion in the last 3 months.
Order anytime; kit dispatched within 24 hours Mon–Fri.
Allow 24–48 hours for sample transit on top of lab processing time.
Adults 18+ within 20 miles of a serviced city centre.
Mon–Sun, 06:00–20:00. Next-day booking typical.
Sample reaches the lab within 24 hours of collection.
Adults 16+ with photo ID. Paediatric draws by appointment at selected sites.
Mon–Fri, with Saturday hours at most metropolitan locations.
Samples processed same-day at the receiving clinic.
Every test is processed in a UKAS ISO 15189-accredited laboratory, overseen by GMC-registered physicians, and governed by UK GDPR. No overseas processing, no offshore data.
Follow these guidelines to ensure accurate, reproducible results. Most markers are sensitive to recent food, exercise, and sleep.
Can't find your answer? Our clinical support team is available Monday to Friday, 9am–5pm.
Contact supportPolycystic ovary syndrome (PCOS) is a hormonal condition affecting around 1 in 10 women of reproductive age in the UK. Despite its name, it does not necessarily involve cysts on the ovaries — the term refers to the appearance of multiple follicles on ultrasound. PCOS is characterised by a combination of symptoms including irregular or absent periods, signs of androgen excess (acne, unwanted hair growth, hair thinning), and metabolic features such as insulin resistance and weight gain. It is the most common cause of female infertility due to anovulation.
Insulin resistance means the body’s cells respond poorly to insulin, causing the pancreas to produce more of it to maintain blood glucose control. Elevated insulin directly stimulates the ovaries to produce more androgens (particularly testosterone), disrupting normal follicle development and ovulation. High insulin also reduces SHBG, further increasing free androgen activity. Addressing insulin resistance through diet, exercise, or medication such as metformin is therefore a central component of PCOS management — not just for metabolic health but for normalising the hormonal picture.
In women with PCOS, LH is often elevated relative to FSH — a ratio greater than 2:1 or sometimes 3:1 is classically described. This elevated LH drives androgen production from the ovarian theca cells and disrupts the hormonal signalling required for normal ovulation. However, LH is highly pulsatile and a normal LH-to-FSH ratio does not exclude PCOS, since it may be normal in up to 40% of women with confirmed PCOS. The ratio is one data point to consider alongside the full hormonal and clinical picture.
Dehydroepiandrosterone Sulphate (DHEA-S) is an androgen produced by the adrenal glands rather than the ovaries. In PCOS, androgen excess is typically of ovarian origin (elevated testosterone, normal or mildly elevated dehydroepiandrosterone sulphate (DHEA-S)). If dehydroepiandrosterone sulphate (DHEA-S) is markedly elevated, this suggests a significant adrenal contribution to the androgen excess, which changes the differential diagnosis and may point to late-onset congenital adrenal hyperplasia or, less commonly, an adrenal tumour. Including dehydroepiandrosterone sulphate (DHEA-S) allows the physician to characterise the source of androgen excess more precisely.
This panel will provide the biochemical evidence that contributes to a PCOS assessment, but a formal diagnosis requires clinical assessment, symptom history, and often a pelvic ultrasound. Under the Rotterdam criteria, PCOS is diagnosed when two of three features are present: irregular cycles, biochemical or clinical androgen excess, and polycystic ovarian morphology on ultrasound. Your Trupoint Health physician report will interpret the blood results and advise on appropriate next steps, including whether a GP consultation or gynaecology referral is recommended.
Yes, significantly. Insulin resistance is highly modifiable through dietary changes — particularly reducing refined carbohydrates and added sugars, increasing fibre and protein, and adopting a lower glycaemic index eating pattern. Regular moderate exercise improves insulin sensitivity. These changes can reduce fasting insulin, lower free testosterone, increase SHBG, and improve LH-to-FSH ratios in a matter of months. Many women see meaningful improvement in their blood results after 3 to 6 months of consistent lifestyle modification, with corresponding improvements in cycle regularity and symptom burden.
